Scope
Molecular engineering in medicine is a bottom-up approach to making functional materials and devices for biomedical diagnosis and therapy development. It is highly interdisciplinary, bridging physical sciences, biology, engineering, and medical sciences. Recent advances in this field, such as the development of COVID-19 vaccines, genetically modified organ transplants and other forms of tissue engineering, stem-cell therapy, immunotherapy, and gene editing have significantly impacted biomedical research, the biotech industry, and healthcare practice. This special issue invites submissions of both original Research and Review articles covering advanced biotechnologies within all aspects of molecular engineering.
The topics the special issue specifically seeks to cover include (but are not limited to):
- Biomaterials
- Regenerative medicine
- Tissue engineering
- Organ on a chip
- Bioprinting
- Drug delivery
- Immuno-engineering
- Protein engineering
- Gene editing
- Drug discovery, design, and screening
- Biologics
Guest Editors
Xiaohu Gao
Professor
Department of Bioengineering
University of Washington
Seattle, WA, 98195
Warren L Grayson
Professor and Vice-Chair for Faculty Affairs
Department of Biomedical Engineering
Johns Hopkins University
Baltimore, MD 21218
Zhongze Gu
Professor and Director of State Key Lab of Bioelectronics
Southeast University
Nanjing, Jiangsu, China
Submission Instructions
Please select "Special Issue: Molecular Engineering and Regenerative Medicine" as the section/category during the submission process. Please also indicate in your cover letter that your submission is intended for inclusion in the special issue.
Submission Deadline: September 30, 2023
Table of Contents
The interest in using therapeutic nanoparticles to bind with harmful molecules or pathogens and subsequently neutralize their bioactivity has grown tremendously. Among various nanomedicine platforms, cell membrane-coated nanoparticles, namely, “cellular ...
Treatments for disease in the central nervous system (CNS) are limited because of difficulties in agent penetration through the blood-brain barrier, achieving optimal dosing, and mitigating off-target effects. The prospect of precision medicine in CNS ...
The effective treatment of patients with cancer hinges on the delivery of therapeutics to a tumor site. Nanoparticles provide an essential transport system. We present 5 principles to consider when designing nanoparticles for cancer targeting: (a) ...
We need novel strategies to target the complexity of cancer and, particularly, of metastatic disease. As an example of this complexity, certain tissues are particularly hospitable environments for metastases, whereas others do not contain fertile ...
Vascular prostheses (grafts) are widely used for hemodialysis blood access, trauma repair, aneurism repair, and cardiovascular reconstruction. However, smaller-diameter (≤4 mm) grafts that would be valuable for many reconstructions have not been achieved ...