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Advanced Biofabrication and Biomaterials for Regenerative Medicine

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Scope

Regenerative medicine seeks to repair or replace damaged, diseased, and senile human tissues/organs. To achieve this objective, viable strategies include but are not limited to the production of functional tissue/organ implants, delivery of drugs/biomolecules, cell therapy, and interventional biomedical devices. A common prerequisite of these approaches is the precise orchestration of multiple fragile cellular/molecular components to build the pre-designed construct. In addition, it is also critical to select appropriate biomaterials that can escort the payloads toward the target sites, as well as facilitating the therapeutic and pharmaceutical process. Hence, the development of advanced biofabrication technologies and versatile biomaterials holds the top priority among all current challenges in the field of regenerative medicine. 

In the past decades, diverse novel biofabrication technologies (e.g., electrospinning, microfluidics, 3D bioprinting, and micro/nano-robotic bio-assembly) and functional biomaterials (e.g., ECM-mimicking materials, stimuli-responsive materials, and shape-memory materials) have emerged and significantly accelerated the advancement of regenerative medicine. However, despite the considerable achievements and great potential, a majority of current research is still in the infant stage, far from clinical applications. With the emergence of the fourth industrial revolution, the trend of future medical technology has been rapidly changed.

This Special Issue aims to provide an opportunity for researchers to contribute their latest research regarding the developments and applications of advanced biofabrication and biomaterials for regenerative medicine. Topics include but are not limited to the following:

  • Biofabrication of tissue/organ analogues
  • Novel multi-scale biofabrication strategies
  • In vitro tissue/organ/disease modelling
  • In vivo applications of tissue engineered constructs
  • 4D bioprinting of intelligent structures
  • Programmable drug delivery systems
  • Biomanufacturing of advanced biomedical devices
  • Smart biomaterials for regenerative medicine
  • Formulation of functional bioinks

Guest Editors

Dr. Michael Gelinsky, Professor, Technische Universität Dresden

Portrait of Dr. Michael Gelinsky Dr. Michael Gelinsky is Professor and Head of the Centre for Translational Bone, Joint and Soft Tissue Research at the Faculty of Medicine of Dresden University of Technology (TU Dresden), Germany. He studied chemistry at the University of Freiburg (Germany) and obtained his PhD there in 2001. Before being appointed as professor he was heading a research lab at the Max Bergmann Center of Biomaterials of TU Dresden. He is Fellow of Biomaterials Science and Engineering (FBSE). Currently he is member of the Board of Directors of the International Society for Biofabrication (ISBF) and President of the German Society for Biomaterials (DGBM).

Dr. Jinhua Li, Professor, Beijing Institute of Technology

Portrait of Dr. Jinhua Li Dr. Jinhua Li is Professor of Beijing Institute of Technology (BIT), Fellow of Alexander von Humboldt Stiftung, Teli Young Fellow of BIT, and Vebleo Fellow. He is the Responsible Professor in Medical Materials and Tissue Engineering. He was Awardee of Marie Skłodowska-Curie Individual Fellowship (MSCA-IF). His research interests include biomaterials, 3D printing, tissue engineering, regenerative medicine, intelligent drug delivery, and bioimaging. Up to now, he has published over 50 SCI papers in Chemical Society Reviews, Advanced Materials, Materials Today, Materials Science and Engineering: R: Reports, Advanced Functional Materials, Advanced Science, Materials Horizons, Biomaterials, and other journals with the h-index of 30 and total citations of more than 2800 (Google Scholar).

Dr. Jinah Jang, Associate Professor, Pohang University of Science and Technology

Portrait of Dr. Jinah Jang Dr. Jinah Jang is an Associate Professor of Convergence IT Engineering and Mechanical Engineering departments at Pohang University of Science and Technology. She has published more than 100 peer-reviewed articles in prestigious journals in the area of bioprinting and tissue engineering (h-index: 39, citations > 6,260). She currently serves as the Associate Editor of Bio-Design and Manufacturing and as a board of directors for International Society for Biofabrication. She also has received numerous awards including the SME Outstanding Young Engineer Award (2022). Her research interest lies in engineering the functional human tissues using high-performance stem cells and 3D bioprinting technology.

Dr. Liliang Ouyang, Assistant Professor, Tsinghua University

Portrait of Dr. Liliang Ouyang Dr. Liliang Ouyang is currently an Assistant Professor in the Department of Mechanical Engineering at Tsinghua University (llouyang.com). He obtained a Ph.D. degree in Materials Science and Engineering at Tsinghua University (2017), postdoctoral training in Materials and Bioengineering at Imperial College London (2017-2020), and a visiting research training in Bioengineering at the University of Pennsylvania (2015-2016). His research interests include the design, fabrication, and application of complex biomaterial and cellular systems, with a central focus on the development of 3D bioprinting and advanced biofabrication technologies for engineering in vitro living systems. He has published a series of peer-reviewed articles in well-recognized journals, including Science Advances, Advanced Materials, Materials Today, Trends in Biotechnology, and Advanced Functional Materials, with three ESI Highly Cited research articles. He currently serves as an Associate Editor of the International Journal of Bioprinting and an Early Career Researcher committee member of ISBF. He has been recognized with a series of awards, including the ISBF New Investigator Award (2021), IOP Top Cited Author Award (2018), Distinguished Doctorate of Tsinghua University (2017), and GE Foundation TECH Award First Place (2016).

Dr. Ge Gao, Assistant Professor, Beijing Institute of Technology

Portrait of Dr. Ge Gao Dr. Ge Gao received his PhD at the Department of Mechanical Engineering at POSTECH in 2019 and worked as a postdoctoral fellow until 2020 in Prof. Dong-Woo Cho’s lab. He joined Beijing Institute of Technology in the end of 2020 as an assistant professor in the School of Medical Technology. His research focuses on novel 3D bioprinting strategies, formulation of innovative bioinks, as well as building tissue/organ equivalents, in vitro disease modeling, and organ-on-a-chip for the applications in regenerative medicine, analytics, and diagnostics. The achievements have been published in over 20 top journals, including Advanced Functional Materials, Biomaterials, Biofabrication, Applied Physics Reviews, Small Methods, and other high impact journals.

Submission Instructions

Please select "Special Issue: Advanced Biofabrication and Biomaterials for Regenerative Medicine" as the section/category during the submission process. Please also indicate in your cover letter that your submission is intended for inclusion in the special issue.

Submission Deadline: June 30, 2023

Table of Contents

    • By
      • Min Ye
      • Yan Zhou
      • Hongyu Zhao
      • Xiaopu Wang
    Untethered microrobots can be used for cargo delivery (e.g., drug molecules, stem cells, and genes) targeting designated areas. However, it is not enough to just reach the lesion site, as some drugs can only play the best therapeutic effect within the ...
    • By
      • Xinmeng Li
      • Weixiao Ding
      • Shujun Wang
      • Luyu Yang
      • Qingqing Yu
      • Changji Xiao
      • Guangbo Chen
      • Lei Zhang
      • Shanyue Guan
      • Dongping Sun
    The liver is the hub of human metabolism and involves many diseases. To better work on the mechanism and treatment of liver diseases, it is of particular interest to design 3-dimensional scaffolds suitable for culturing hepatocytes in vitro to simulate ...
    • By
      • Chen Zhao
      • Jun Kang
      • Yuwen Li
      • Yan Wang
      • Xiaoying Tang
      • Zhenqi Jiang
    Carbon-based nanomaterials, including carbon nanotubes, carbon nanospheres, and carbon nanofibers, are becoming a research hotspot due to their unique structure and good mechanical, thermal, electrical, optical, and chemical properties. With the ...
  • In the last decade, organoids have gained popularity for developing mini-organs to support advancements in the study of organogenesis, disease modeling, and drug screening and, subsequently, in the development of new therapies. To date, such cultures have ...
    • By
      • Huaijuan Zhou
      • Guozhao Dong
      • Ge Gao
      • Ran Du
      • Xiaoying Tang
      • Yining Ma
      • Jinhua Li
    The rapid development of medical micromotors draws a beautiful blueprint for the noninvasive or minimally invasive diagnosis and therapy. By combining stimuli-sensitive hydrogel materials, micromotors are bestowed with new characteristics such as stimuli-...