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Advanced Ultrasound Technologies and Biomedical Applications
Scope
Ultrasound is a non-invasive imaging technology that is widely used for examination in clinical medicine and also as an important tool for research. Diagnostic ultrasound as well as ultrasound guidance for biopsy and tumor ablation have become integral in clinical instrumentation. Recently, there has been an increase in new ultrasound techniques such as high-resolution contrast enhanced ultrasound, micro-elastography techniques, 3D ultrasound, plane wave imaging, high frequency ultrasound, and ultrasound modulation. In addition, therapeutic ultrasound, such as high intensity focused ultrasound (HIFU), histotripsy, ultrasound drug delivery, ultrasound-enhanced immunotherapy, sonothrombolysis, and ultrasound neuromodulation, has made significant progress technically, scientifically, and clinically. This special issue invites submissions of both original research and review papers covering advanced ultrasound technologies within all aspects of advanced ultrasound.
- The topics we specifically seek to cover include (but are not limited to):
- 3D ultrasound
- Blood flow Imaging
- Contrast enhanced ultrasound
- Elasticity imaging
- HIFU technology
- High frequency ultrasound
- Histotripsy
- Novel ultrasound transducer/arrays
- Plane wave imaging
- Sonothrombolysis
- Ultrasound drug delivery
- Ultrasound modulation
- Ultrasound-enhanced immunotherapy
Guest Editors
Qifa Zhou
University of Southern California
Zhen Xu
University of Michigan
Joo Ha Hwang
Stanford University
K Kirk Shung
University of Southern California
Table of Contents
- Objective. This paper is an initial work towards developing particle-mediated histotripsy (PMH) as a novel method of treating catheter-based medical device (CBMD) intraluminal biofilms. Impact Statement. CBMDs commonly become infected with bacterial ...
- Objective and Impact Statement. This study examined the efficacy and safety of pulsed, low-intensity focused ultrasound (LIFU) and determined its ability to provide neuroprotection in a murine permanent middle cerebral artery occlusion (pMCAO) model. ...
- 3D photoacoustic computed tomography (3D-PACT) has made great advances in volumetric imaging of biological tissues, with high spatial-temporal resolutions and large penetration depth. The development of 3D-PACT requires high-performance acoustic sensors ...
- Objective. To develop a 3D shear wave elastography (SWE) technique using a 2D row column addressing (RCA) array, with either external vibration or acoustic radiation force (ARF) as the shear wave source. Impact Statement. The proposed method paves the way ...
- Objective and Impact Statement. Simultaneous imaging of ultrasound and optical contrasts can help map structural, functional, and molecular biomarkers inside living subjects with high spatial resolution. There is a need to develop a platform to facilitate ...
- Large aperture ultrasonic arrays can be implemented by tiling together multiple pretested modules of high-density acoustic arrays with closely integrated multiplexing and buffering electronics to form a larger aperture with high yield. These modular ...
- The purpose of this study is to develop a method for delivering antiinflammatory agents of high molecular weight (e.g., Avastin) into the posterior segment that does not require injections into the eye (i.e., intravitreal injections; IVT). Diseases ...
- Ultrasound ablation techniques are minimally invasive alternatives to surgical resection and have rapidly increased in use. The response of tissue to HIFU ablation differs based on the relative contributions of thermal and mechanical effects, which can be ...
- Objective and Impact Statement. To develop an approach for individualized closed-loop feedback control of microbubble cavitation to achieve safe and effective focused ultrasound in combination with microbubble-induced blood-brain barrier opening (FUS-BBBO)...
- Objective. Retinal degeneration involving progressive deterioration and loss of function of photoreceptors is a major cause of permanent vision loss worldwide. Strategies to treat these incurable conditions incorporate retinal prostheses via electrically ...
- Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma membrane perforation, is well considered as an emerging physical approach to facilitate the delivery of drugs and genes to living cells. Nevertheless, this ...
